Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p192 | (1) | WCRB2014

Effect of melatonin supplementation during in vitro maturation on intracellular ROS levels in porcine oocytes

Cruz Maria Helena Coelho , Cruz Jurandir Ferreira , Reiter Russel J , Schwarz Katia Lancellotti , Castro Fernanda Cavallari , Cunha Maria Carolina R V , Verde Leal Claudia Lima

Oocytes of domestic mammals present high concentrations of lipids, and this is particularly evident in porcine oocytes that exhibit higher levels than other species, becoming more susceptible to oxidative stress and lipid peroxidation. Considering that melatonin is an effective antioxidant for protecting macromolecules against oxidative stress caused by reactive oxygen species (ROS), the purpose of the present study was to examine the effect of melatonin supplementation during...